Bouziane HoudaEncadreur: KASSAH L. A.2024-07-162024-07-162013579/101-T PDFhttp://dspace.univ-khenchela.dz:4000/handle/123456789/6007This study focused on strains of Enterobacteriaceae producing betalactamases extended spectrum (ESBL) in the central laboratory of Microbiology of the University Hospital of Batna and laboratory Grande Clinic Mezdaouet Khenchela. These strains were isolated from various samples (urine, blood, pus) has been the subject of a classic study with enrichment steps, isolation and identification. 53 strains belonging to four species were divided according to several parameters (sampling, age, sex, month and services). Klebsiella spp is the most isolated (47%) species, followed by Escherichia coli (28%). The majority of strains were isolated from pus, in men, in patients aged birth to nine years in service burned in two and a half months of 2013. The ESBL-producing strains are usually hospital (75%) compared to external strains (25%). The synergy between AMC records and C3G obtained by several techniques (Double disc (Spanish test), reconciliation and cloxacillin disk test).frThesis