Green Synthesis of Azomethine Compounds
| dc.contributor.author | GOLEA, Lynda | |
| dc.date.accessioned | 2026-09-28T09:46:37Z | |
| dc.date.available | 2026-09-28T09:46:37Z | |
| dc.date.issued | 2026 | |
| dc.description.abstract | This work presents the synthesis and spectroscopic characterization of three azomethine derivatives also known as Schiff bases, obtained by condensation of two aromatic amines (4-aminophenol and sulfanilamide) with two carbonyl compounds (benzaldehyde and acetophenone) under eco-friendly conditions. The reactions were carried out under reflux in ethanol using acetic acid as a catalyst, in accordance with the principles of green chemistry. The three synthesized compounds (SB1-SB3) were characterized by Thin-Layer Chromatography (TLC), UV–Visible spectroscopy, Fourier-Transform Infrared spectroscopy (FT-IR), and Proton Nuclear Magnetic Resonance (¹H NMR) spectroscopy. The formation of the imine bond (C=N) was confirmed in each case by the disappearance of the carbonyl C=O stretch and primary amine N–H bands in the FT-IR spectra, and by the characteristic azomethine proton signal in the ¹H NMR spectra. For the sulfanilamide-derived compound (SB-3), the reaction proceeded selectively at the primary aromatic amine group rather than at the less nucleophilic sulfonamide nitrogen. The results confirm that TLC, UV–Vis, FT-IR, and ¹H NMR together constitute a reliable and complementary toolkit for structural elucidation of azomethine compounds. The synthesized Schiff bases represent promising candidates for further investigation of their biological and coordination chemistry properties. | |
| dc.identifier.uri | http://dspace.univ-khenchela.dz:4000/handle/123456789/11444 | |
| dc.language.iso | en | |
| dc.title | Green Synthesis of Azomethine Compounds | |
| dc.type | Thesis |