(4S)-4-Benzyl-N-{[(4S)-4-benzyl-2-oxo-1,3-oxazolidin-3yl]sulfonyl}-2-oxo-1,3-oxazolidine-3-carboxamide
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Date
2010-06-01
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Abstract
The title compound, C
21
H
21
N
3
O
S, contains an oxazolidinone
ring and a sulfonamide group, both characteristic for
biologically and pharrmaceutically active compounds. Both
stereogenic centres reveal an S absolute configuration. The
two oxazolidinone rings are in an envelope conformation with
the methylene carbon flap atoms deviating by 0.428 (1) and
0.364 (2) A
7
˚
from the best least-square planes formed by the
four other ring atoms. An intramolecular N—H O hydrogen
bond contributes to the folded conformation of the molecule.
In the crystal, weak intermolecular C—H O interactions
connect the molecules into helices along the the twofold screw
axes.