Synthesis, Characterizations, and Biological Effects Study of Some Quinoline Family

dc.contributor.authorMessai Amel
dc.date.accessioned2024-02-18T16:56:02Z
dc.date.available2024-02-18T16:56:02Z
dc.date.issued2016
dc.description.abstractThe objective of this work is the synthesis of new quinoline molecules which could have some biological activities. This chapter reported a new approach to the synthesis of some quinoline derivatives. The Baylis-Hillman reaction on 2-methoxy-3-formyl quinoléines derivatives have applied in order to obtain Baylis-Hillman adducts. The products are characterized by FTIR, NMR and X-ray single crystal diffraction .Also, a study of the antibacterial activity of the 3-(2-chloro quinoline)-3-hydroxy-2 methylene propanonitrile products synthesized have been explored. This assessment is made by using the disk diffusion method. The results showed that the 3-(2’-chloroquinoline)-3-hydroxy-2-methylenepropanonitril derivatives present a good antibacterial effectiveness against the strains tested Gram-positive and no antibacterial potency was observed against the stains Gram-negative used in the test.
dc.identifier.urihttp://dspace.univ-khenchela.dz:4000/handle/123456789/1488
dc.language.isoen
dc.titleSynthesis, Characterizations, and Biological Effects Study of Some Quinoline Family
dc.typeArticle
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