Acute Toxicity Study of Abies numidica Extracts in Broiler Chickens
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Date
2021-12-24
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Indian Journal of Novel Drug Delivery
Abstract
The aim of this study was to assess in vivo acute toxicity of hydroalcoholic and
aqueous extracts of Algerian fir needles (Abies numidica) in broiler chickens. Total
18 one-day-old broiler chicks were obtained from hatchery. At three weeks of age
chickens were weighed and separated into 3 groups. The control group received
only distilled water, while treatment groups were orally administered 2000
mg.kg-1b.wt. of hydroalcoholic and aqueous extracts of Abies numidica. No
mortality or significant changes were observed in body weight, feed intake and
feed conversion. Also, Blood parameters and relative organ weights were normal.
Microscopic observations of liver and kidneys tissues of treatment and control
group were similar. In conclusion, acute toxicity test indicated that extracts were
not toxic when administered by the oral route to broiler chickens at 2000
mg.kg1b.wt.