In vitro antimicrobial activity of Salvadora persica and Juglans regia extracts against microbial strains from oral cavity

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used for the oral hygiene in Arabic countries. Four extracts prepared with organic solvents of increasing polarity; petroleum ether, chloroform, ethyl acetate, and methanol were used to test the antibacterial and antifungal activities of these plants with three different concentrations of each extract; 5, 10 and 15mg/ml. The results showed that Juglans regia seems to be more efficient against the isolated strains than Salvadora persica. Moreover the ethyl acetate extract of J. regia showed a high degree of antimicrobial activity. Forty bacterial isolates were identified from the oral cavity of healthy individuals of different age categories (from 10 to 44 years) and only seven isolates were selected and characterized as Staphylococcus saprophyticus (B1), Proteus vulgaris (B2), Pseudomonas aeruginosa (B3), Staphylococcus aureus (B4), Serratia marcescens (B5), Streptococcus salivarius (B6), Streptococcus mutans (B7) and a yeast species identified as Candida albicans (Y). The highest efficiency of all extracts of the two plants achieved with Streptococcus mutans (mean of diameters of inhibition zones MDIZs = 10.29mm) followed by Streptococcus salivarius (MDIZs = 9.75mm), Candida albicans (MDIZs = 6.45mm), Proteus vulgaris (MDIZs = 5.75mm), Staphylococcus aureus (MDIZs = 5.62mm), Serratia marcescens (MDIZs = 5.58mm), Pseudomonas aeruginosa (MDIZs = 4.87mm) and Staphylococcus saprophyticus (MDIZs = 3.08mm).