Synthesis, Characterizations, and Biological Effects Study of Some Quinoline Family
| dc.contributor.author | MESSAI Amel | |
| dc.date.accessioned | 2024-02-13T19:42:47Z | |
| dc.date.available | 2024-02-13T19:42:47Z | |
| dc.date.issued | 2016 | |
| dc.description.abstract | The objective of this work is the synthesis of new quinoline molecules which could have some biological activities. This chapter reported a new approach to the synthesis of some quinoline derivatives. The Baylis-Hillman reaction on 2-methoxy-3-formyl quinoléines derivatives have applied in order to obtain Baylis-Hillman adducts. The products are characterized by FTIR, NMR and X-ray single crystal diffraction .Also, a study of the antibacterial activity of the 3-(2-chloro quinoline)-3-hydroxy-2 methylene propanonitrile products synthesized have been explored. This assessment is made by using the disk diffusion method. The results showed that the 3-(2’-chloroquinoline)-3-hydroxy-2-methylenepropanonitril derivatives present a good antibacterial effectiveness against the strains tested Gram-positive and no antibacterial potency was observed against the stains Gram-negative used in the test. | |
| dc.identifier.uri | http://dspace.univ-khenchela.dz:4000/handle/123456789/761 | |
| dc.title | Synthesis, Characterizations, and Biological Effects Study of Some Quinoline Family |