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Item Article original Incidence du streptocoque du groupe b (sgb) chez les nouveau-nés nés à Constantine (Algérie) et dans deux de ses banlieues. Intérêt de la détermination des sérotypesIncidence of group b streptococcus (gbs) in neonates born in Constantine (Algeria) and two of its suburbs usefullness of serotyping(elsevier, 2003-08) M. A. HAMIDECHIAim. – Group B Streptococcus (GBS) is the germ most often responsible for neonatal infections. Several risk factors are described. The objective of this investigation was to demonstrate the effects of age, sex, and place of birth in neonates GBS infection, including serotype distribution. Method. – A 4 years-long multicentric study was carried out in Constantine and 2 of its suburbs, including 8,711 live neonates. Seven hundred and thirty-three suspected infections were recorded and sorted according to postnatal age (≤ 7 days and > 7 days), sex, and place of birth (related to the mothers’ socioprofessional status). Thirty-one cases of GBS infection were confirmed. Results. – GBS was identified in 53 out of 733 suspected cases of infection (i.e.: 7.2% or 1/14 suspected case). The incidence of early GBS infection was greater than late onset (36 vs 17 out of 53 cases). GBS colonization was not related to age. High socioprofessional status decreased the infection risk significantly in neonates. Conclusion. – This study demonstrates that favorable hygiene and the mother’s high socioprofessional status decrease the risk of neonatal GBS infectionItem Présence de Dasypoda maura Perez, 1895, en Algérie (Hym., Apoidea, Melittidae)(researchgate, 2007-01) Maghni NoudjoudLes Hyménoptères Melittidae, notamment ceux du genre Dasypoda Latreille, 1802, sont très répandus dans la région paléarctique. Cependant, les travaux se rapportant à l’Algérie et qui datent de la première moitié du 20e siècle mentionnent uniquement la présence de 6 espèces : Dasypoda brevicornis (Rossi, 1791), D. hirtipes (Fabricius, 1793), D. plumipes (Panzer, 1797), D. cingulata Erichson, 1835, D. sinuata Pérez, 1855 et D. oraniensis Perez, 1895 (SAUNDERS, 1901, 1908 ; ALFKEN, 1914 ; BENOIST, 1924, 1961 ; MORICE, 1916 ; ROTH, 1923, 1924 ; SCHULTHESS, 1924). Dans les travaux les plus récents, LOUADI & DOUMANDJI (1998 a et b) ont noté l’absence des Melittidae dans la région de Constantine. En 2003, MATALLAH relève dans la région de Skikda (36°53’ N, 6°55’ E, 42 m) la présence de Dasypoda visnaga Rossi, 1790, qui présente une distribution méditerranéenne. Au cours de nos prospections menées du 3 juin au 17 juillet 2005 dans la wilaya de Khenchela, plus exactement au mont Chelia à 2176 m (35°20’ N et 60°39’ E, nous avons récolté 24 spécimens de D. maura Perez, 1895, qui n’était connue jusqu’à présent que du Maroc (MICHEZ et al., 2004 a, b). Cette espèce fréquentait deux plantes spontanées de la famille des Asteraceae (Sylibum marianum L., 6 spécimens, et Echinops spinosus L., 18 spécimens). Cette présence au mont Chelia montre sans aucun doute que cette espèce nouvelle pour l’Algérie a une répartition plus large. D’autres investigations en cours dans des régions limitrophes nous renseigneraient certainement davantage sur sa distribution géographique.Item Les Hyménoptères Apoidea de l’Algérie orientale avec une liste d'espèces et comparaison avec les faunes ouest-paléarctiques(researchgate, 2008-01) Noudjoud MAGHNIHymenoptera Apoidea of eastern Algeria and comparison with western Palaearctic fauna. Our own investigations in North Eastern Algeria and data from other authors revealed the presence of 382 species of Bees belonging to 55 genera.These species were distributed into six families: Colletidae (2 genera, 25 species), Melittidae (3 genera, 9 species), Halictidae (8 genera, 60 species), Andrenidae (5 genera, 77 species), Apidae (17 genera, 111 species) and Megachilidae (20 genera, 100 species). Compared to the west Palaearctic fauna, long tongued Bees were more represented with 211 species against 171 for those with a short tongue in Algeria. In West Palaearctic the short tongued Bees constituted the majority: 253 species in Baden-Wurtenberg (Germany) against 137 long tongued species. There is a greater number of Megachilini and Osmiini (Megachilidae) in Algeria whereas in Western Europe, Bumblebees of the genus Bombus (Bombini, Apidae) are the most diverse.Item Étude du profil épidémiologique et des facteurs de risque alimentaires du cancer du nasopharynx dans le Nord-Est algérien(springer, 2010-12-06) BENDJEMANA KATIANasopharyngeal carcinoma (NPC) is one of the most important cancers in Algeria with 8 to 12 cases/ 100,000 persons a year. The pathogenesis of NPC is not clear. In Algeria and Tunisia, it represents the first most common cancer of the larynx in women and the second most common tumor inmen. This is a retrospective epidemiological study of the NPC in the North-East of Algeria and evaluates the impact of the consumption of some foods, tobacco and alcohol on the risk of development of NPC. The study of a group of 160 patients affected by NPC, using 205 people as a control group, has shown that this cancer was predominant in men, particularly in the population between 40- and 59-years-old. The analysis has shown that preservatives such askhliiseem to be a statistically significant factor related to NPC. Our results also show a strong association between alcohol consumption and tobacco use and the risk of developing NPC. However, we did not find a statistically significant relationship with other food factors. Résumé Le carcinome du nasopharynx (CNP) représente un des cancers les plus importants dans notre pays, avec une incidence moyenne de 8 à 12 cas/100 000 habitants par an. Il représente en Algérie et en Tunisie le premier cancer des voies aérodigestives chez la femme et le deuxième après le cancer du larynx chez l’homme. L’étiologie de ce cancer incrimine trois types de facteurs: le facteur viral, les facteurs génétiques et environnementaux, notamment alimentaires et tabagiques. Le but de notre travail rétrospectif est d’évaluer le profil épidémiologique du cancer du nasopharynx au niveau des régions de Khenchela et de Batna et leurs environs et d’identifier les aliments à risque pour le CNP. L’étude a concerné 160 patients ayant un CNP de type UCNT (undifferentiated carcinoma of nasopharyngeal type) recensés dans les régions et 205 témoins appariés aux malades selon l’âge, le sexe et la région géographique. Les résultats montrent que ce cancer prédominait particulièrement chez les hommes, avec une forte incidence pour la tranche d’âge de 40 à 60 ans. L’analyse des facteurs alimentaires et tabagiques montre un risque élevé de CNP lié significativement à la consommation de produits de conservation traditionnelle tels que le khlii et les saumures. Nos résultats montrent aussi une forte association entre la consommation d’alcool et de tabac et le risque de développement du CNP. Cependant, cette association n’a pas pu être démontrée pour le reste des aliments faisant l’objet de notre étude.Item La dynamique agricole dans la zone d'El Ghrous (Biskra) : entre le boom maraîcher et la lente généralisation des systèmes de production phoenicicoles(2011) Laiche AouidaneIn the current study we investigate the farming system development in the region of El Ghrous (Biskra), through evolution trend of three identified farm kinds (palm, truck farming, and mixed). The result show that the evolution of the old farms began with a partial occupation of land by the date palm followed by an introduction and extension Plasticulture then became a holding palm where other crops are marginalized. The truck farming system production in the region is profitable and has been widespread, but remains cyclical and tends to be replaced by the mixed systems (phoeniculture –gardening) to become a purpose – palm.Item Incidence de Listeria spp. et autres bactéries psychrotrophes dans le lait cru bovin dans le Nord Est Algérien(researchgate, 2011-01) M. A. HAMIDECHIIn this study a total of 104 milk samples collected from 60 dairy cattle in six farms in the North East part of Algeria were examined for the presence of Listeria spp. and other psychrotrophic bacteria. The isolation was accomplished by cold storage of milk samples followed by plating on blood agar added of Cefazoline. The isolates were identified phenotypicaly by studying cultural, morphological, biochemical criteria; and genotypicaly using the 16S rRNA gene. Psychrotrophic bacteria from numerous genera have been isolated, both gram negative “Acinetobacter spp., Aeromonas spp., Pseudomonas spp., Stenotrophomonas spp., Proteus spp., Yersinia spp., Klebsiella spp., Alcaligenes spp., and Flavobacterium spp.” and gram positive “Enterococcus spp., Listeria spp., Staphylococcus spp., and Bacillus spp.”. Enterococcus spp. was the dominant genera in different seasons. Milk contamination by Listeria spp. was seasonal, its incidence was positive in winter and in spring, however it was absent in summer and autumn.Item IMPROVEMENT OF SALT TOLERANCE IN DURUM WHEAT BY ASCORBIC ACID APPLICATION(Journal of Stress Physiology & Biochemistry, 2011-01-07) Azzedine FerchaThe main objective of this study is to examine whether exogenously applied Ascorbic acid (AsA) may enhance the salt tolerance in durum wheat (Triticum durum Desf. var. Waha). Two weeks old seedling, grown in plastic pots of 1kg, were subjected to salt stress by adding 25ml of NaCl (150mm), and treated or not with the addition of ascorbic acid (0.7 mM). Two weeks after salt stress, plants were harvested and the various measures were recorded. The effects of salt stress, in the presence and absence of vitamin C, on the leaf growth, leaf area (LA) and some physiological and biochemical changes were investigated. It was established that the application of vitamin C mitigate to variable extent the adverse effect of salt stress on plant growth, may be due, in part, to increased leaf area, improved chlorophyll and carotenoid contents, enhanced proline accumulation and decreased H2O2 content. In conclusion, we can say that treatment with ascorbic acid improve salt tolerance in durum wheat through the enhancement of multiple processes.Item CONTRIBUTION DU DIAGNOSTIC BIOCHIMIQUE BACTERIEN DANS L’ETABLISSEMENT DES PARENTES PHYLOGENETIQUES : CAS DES Enterobacteriaceae ET Pseudomonas sp(Sciences& Technologie, 2011-12) M. A. HAMIDECHITen bacterial strains were isolated from clinical samples provided by the bacteriology laboratory (Daksi, Constantine). Among the ten strains studied, eight belong to the Enterobacteriaceae and two are among the Pseudomonadaceae. These strains were presumptively identified by their biochemical characteristics, susceptibility or resistance to antibiotics, and total nitrogen measured by the Kjeldahl method. A phylogenetic profile was produced by phenetic methods based on the calculation of genetic distances using the Neighbor Joining algorithm (NJ) and bioinformatics analysis of 16S rRNA sequences to compare the two phylogenies (phenotypic and genotypic). The analysis of topologies obtained showed that the biochemical phenotype has some limitations in bacterial identification and sequence analysis of 16S rRNA is a key tool in bacterial identification across the case.Item Chemical composition and digestibility of some browse plant species collected from Algerian arid rangelands(Spanish Journal of Agricultural Research, 2012) sohil Boufennara; Lyas BouazzaMany wild browse and bush species are undervalued mainly because of insufficient knowledge about their potential feeding value. The objective was to evaluate some nutritional attributes of various Algerian browse and shub species (Atriplex halimus, Artemisia campestris, Artemisia herba-alba, Astragalus gombiformis, Calobota saharae, Retama raetam, Stipagrostis pungens, Lygeum spartum and Stipa tenacissima). Chemical composition, phenols and tannins concentration, in vitro digestibility, in vitro gas production kinetics and in vitro bio-assay for assessment of tannins using buffered rumen fluid, and in situ disappearence of the edible parts of the plants (leaves, thin twigs and flowers) were determined. In general, protein content in dicotyledon species was always greater than in monocotyledon grasses, these showing higher neutral and acid detergent fibre and lower lignin contents than dicots. The tannin concentrations varied considerably between species, but in general the plants investigated in this study had low tannin contents (except for Artemisia spp. and S. tenacissima). Monocots showed lower in vitro and in situ digestibilities, fermentation rate, cumulative gas production and extent of degradation than dicot species. The plants were clustered by principal components analysis in two groups: poor-quality grasses and the most digestible dicot species. Chemical composition (neutral detergent fibre and protein) and digestibility were the main influential variables determining the ranking. In conclusion, A. halimus, A. campestris, A. herba-alba and A. gombiformis can be considered of greater nutritional value than the highly fibrous and low digestible grasses (S. pungens, L. spartum and S. tenacissima) that should be considered emergency roughagesItem Metabolic Diversity of Thermophilic Bacteria from Hot Springs in Algeria(Journal Academica, 2012-03) Wahiba YakhlefABSTRACT Hydrothermal samples have been collected from hot springs in the northeast of Algeria (57– 98°C). The samples in question are considered as extreme ecosystems. The first spring (57°C) have the highest thermophiles isolation rates. Three thermophilic aerobic strains have been purified. The isolates have an optimum growth temperature of about 45 to 70 °C and pH (6.5 – 8.0).The isolates exhibited extracellular amylase, protease and nitrate-reductase activities at high temperature and showed an antibacterial activity against at least one of the test-bacteria studied using the agar cylinder method. The study of their morphological, physiological and biochemical characteristics suggests that these isolates belong to the genera Pseudomonas sp., Thermus sp. and Geobacillus sp. Such studies are needed to understand the microbial communities that are native to the hot springs and their interest in biotechnology.Item Preliminary study to assess cicatrizing activity of honey and Pistacia lentiscus fatty oil mixture on experimental burns in rabbits(researchgate, 2012-08-20) Sofiane HabibatniAbstract: The present study was undertaken to asses cicatrizing activity of a mixture of honey and Pistacia lentiscus fatty oil (PLFO) on dermal burn wounds. It was carried out on 8 male adult New Zealand rabbits. After anesthesia, 4 equal burns were realized on the back of each animal (2 dorsal and 2 lumbar). The wounds were treated, immediately after burning and repeated once daily until 22nd day of experiment, by 0.5 g of honey, 0.5 ml of PLFO or 0.5 g of mixture Honey + PLFO (v/v), the last wound was treated by 0.5 g of Cicatryl® as a reference drug. The healing process was evaluated by calculating the percentage of wound contraction at days 2, 6, 10, 14, 18 and 22. The results showed that both of honey, PLFO and the mixture honey + PLFO promote significantly (P<0.05) the wound contraction when compared to the standard drug at the different time intervals. In addition, PLFO showed better contraction than honey during the inflammatory and proliferative phases. The mixture showed a percentage of wound contraction better than that of honey but lower than that of PLFO used separately during the inflammatory phase, this difference became non significant at day 10 (P>0.05) and marked a significant reduction at the 14th day (P<0.05). After that the differences were not statically significant (P>0.05).In conclusion, the current study suggests that PLFO may ameliorate the healing properties of honey when mixed to it during the inflammatory phase of cicatrizing process in rabbit modelItem Nutritive evaluation of foliage from fodder trees and shrubs characteristic of Algerian arid and semi-arid areas(Journal of Animal and Feed Sciences, 2012-09-14) sohil Boufennara; Lyas BouazzaABSTRACT The chemical composition and digestibility of foliage from nine browse plant species (Artemisia herba-alba, Atriplex halimus, Acacia nilotica, Acacia horrida, Acacia saligna, Faidherbia albida, Albizia julibrissin, Vicia faba and Punica granatum) grown in arid and semi-arid areas of Algeria were evaluated. Feed components were determined by proximate analysis, whereas phenolic and tannin compounds were analysed by colorimetric procedures and their activity tested using a biological assay. Digestibility was assessed by conventional gravimetric in vitro and in situ methods, and rumen fermentation kinetics were estimated from the in vitro gas production technique. The foliage from Acacia species was found to be a protein-rich fodder for ruminants, although the high lignin and tannin content of some species is an important constraint limiting its digestive utilization in the gastrointestinal tract. The leguminous fodder tree, A. julibrissin, has a high protein content and its foliage is highly digestible owing to its low tannin content. Foliage from P. granatum is a highly digestible browse for ruminants.Item To study ways to add a phosphorus on vegetative growth of wheat plants growing under conditions of Algeria(AGRICULTURE AND BIOLOGY JOURNAL OF NORTH AMERICA, 2013) Azzedine FerchaABSTRACT Then a field experiment in two consecutive seasons on a farm in the Division lead to study the effectiveness of the added phosphorus spraying on the leaves and compare them added to the ground on the vegetative growth of wheat plants under conditions of Algeria, where you use three factors for phosphorus P0 - Ps - Pr (without adding phosphorus - affixed to the ground - added spray), respectively. and massage at 50 parts / million P2O5 on the image of super phosphate, and then added in two 3 / 2 amount by the Agriculture mixing with the soil and 3 / 1 the remainder after 15 days of agriculture, was also used phosphorus spraying on the leaves concentration of 1% of the sodium phosphate mono NaHPO4 three periods after 30 - 35 - 40 days of agriculture, and selected two types of soil differ in physical and chemical characteristics, results showed the following: Increased the dry weight of shoot significantly by adding phosphorus to any of the methods for the treatment of comparison, regardless of the type of soil The addition of phosphorus in any of the methods to increase the number of leaves and the back in both two soil in the two phases of growth. The addition of phosphorus to the ground to the significant increase in total dry weight of roots and surpassed the values of dry weight of both shoots and roots in the soil of the first region than those in the soil of Talha. - The mutual influence between the two variables is statistically significantIncreased the total content of phosphorus in shoot dry any of the methods although the added Ground surpassed Added spraying on the leaves, but the same trend was observed for the dry weight of roots.Item Nutritive evaluation of foliage from some Acacia trees characteristic of Algerian arid and semi-arid areas(om.ciheam.org, 2013) Lyas Bouazza; Souhil BoufennaraAbstract. Chemical composition and digestibility of foliage from five Acacia species (Acacia nilotica, Acacia horrida, Acacia saligna, Acacia albida and Albizia julibrissin) from arid and semi-arid areas of Algeria were evaluated. Feed components of proximate analysis were determined, whereas phenolic and tannin compounds were analysed by colorimetric procedures and their activity tested using a biological assay. Digestibility was assessed by conventional gravimetric in vitro and in situ methods, and rumen fermentation kinetics were measured using the in vitro gas production technique. Results showed that all browses contained high levels of CP (157-252 g/kg DM). The content of neutral detergent fiber was highest in A. horrida (551 g/kg DM) and lowest in A. nilotica (290 g/kg DM). The content of lignin was highest in A. saligna (147 g/kg DM). The tannin concentrations varied considerably between species, but in general the plants investigated in this study had high tannin contents. A. nilotica had the highest levels of TP and TET (213 and 205 g/kg DM, respectively). The TCT content ranged from 60 g/kg DM in A. albida to 726 g/ kg DM in A. nilotica. The leguminous fodder tree A. julibrissin shows high protein content and its foliage is highly digestible probably due to its low tannin content. It was concluded that foliage from Acacia species is a protein-rich fodder for ruminants, although the high lignin and tannin content of some species represents an important constraint that could limit digestive utilization in the gastro-intestinal tract of these species.Item The effect of the anticoagulant rodenticide “Brodifacoum” on the bioindicators parameters in male rabbit(Annals of Biological Research, 2013) HICHEM MAAMARThe effect of the anticoagulant rodenticide “Brodifacoum”on the bioindincators parameters inmale domestic rabbits was investigated.Animals were dividedintofourequal groups. The first one served as a control while the otherthree groups weredaily treated by Brodifacoumwithdoses of 0.01, 0.02 and 0.04 mg/kg of body weight. The rodenticide was administered per os for three weeks after which the animals were sacrificed.The obtained results reveal animportant decrease in body weight in treated groupsparticularly in those treated with the highest dose (0.04 mg/kg), whilean increase in the weight of liver was observed, associated with a marked reduction in the weight of spleen and kidney, compared to thecontrol one.Besides,levels of biochemical parameters were also significantly altered.The same observations were made concerning hematological parameters and plasmatic calcium levels in treated animals.Accordingly, it has been concluded thattreatment with Brodifacoum at the used doses and period may alter hematological and biochemical parameters in male rabbits.Item Effect of polyethylene glycol addition on methane production from some Algerian browse plant species in an in vitro gas system(om.ciheam.org, 2013) Lyas Bouazza; sohil BoufennaraAbstract. Biological activity of tannins of different browse plants was measured as the change in methane production when plant material was incubated with and without polyethylene glycol (PEG) using the in vitro gas production technique. Four dicotyledon browse plants (Atriplex halimus, Artemisia campestris, Artemisia herba-alba, Calobota saharae) and three monocotyledon browse plants (Stipagrostis pungens, Lygeum spartum and Stipa tenacissima), collected from an arid zone in Bousâada were evaluated. The increase in gas production upon the addition of PEG, compared with that without PEG, for the browse species varied widely (P<0.05), being particularly high in S. tenacissima (+35.0%) and low in L. spartum (+1.5%). The methane concentration in fermentation gas ranged from 7.9% with A. halimus to 18.6% with L. spartum. The higher increase in methane percentage was noted for S. tenacissima (+47.4%) and the lower percent value was observed for L. spartum (+1.5%). In presence of PEG, the methane production had positive correlation with crude protein (r = +0.78) while in absence of PEG, the methane production was correlated negatively with total condensed tannins (r = -0.88). The strongest correlation (r = 0.89; P<0.01) was between total condensed tannins and methane increase response to the addition of polyethylene glycol, suggesting that tannin compounds appeared to be useful to identify plants possessing antimethanogenic activityItem differential response of durum wheat genotypes to salinity A. Fercha1*, H. Gherroucha2(Journal of Applied Botany and Food Quality, 2013) Azzedine FerchaSummary This study aims to investigate the importance of accumulation of osmoprotectants and activities of some key antioxidant enzymes in genotypic variation (GV) observed among durum wheat genotypes in response to increasing NaCl salinity (0-200 mmol/L) at seedling stage. Germination and seedling growth traits of all the genotypes were significantly decreased by salinity. Mohamed Ben Bachir, the more salt-tolerant genotype, exhibited the lowest reduction in final germination percentage (FGP, <18%) and seedling growth (<60%, based on dry biomass), the lowest increase in proline (PRO) and water soluble carbohydrates contents but the highest increase in catalase (CAT) and ascorbate peroxidase (APX) activities. Correlation and principal components analysis revealed that the most important variables distinguishing salt tolerant vs. salt non-tolerant genotypes were root to shoot ratio (R/S, 36.1%), CAT (30.6%), APX (12.5%) and FGP (5.74%). Although PRO and WSC could play a key role in salt tolerance by mediating osmotic adjustment, these compounds do not seem to be significantly involved in genotypic variation (GV) for salinity tolerance in durum wheat.Item Variability of the dissolved nutrient (N, P, Si) concentrations in the Bay of Annaba in relation to the inputs of the Seybouse and Mafragh estuaries(Elsevier, 2013) Ziouch, Omar RamziDissolved inorganic nitrogen (DIN), phosphate (PO4) and silicic acid (Si(OH)4) loads from the Seybouse and the Mafragh estuaries into the Bay of Annaba, Algeria, were assessed at three stations of the Bay over three years. The Seybouse inputs had high levels of DIN and PO4, in contrast to the Mafragh estuary's near-pristine inputs; Si(OH)4 levels were low in both estuaries. The DIN:PO4 molar ratios were over 30 in most samples and the Si(OH)4: DIN ratio was less than 0.5 in the Seybouse waters, but nearly balanced in the Mafragh. The specific fluxes of Si-Si(OH)4 (400-540 kg Si km 2 yr 1) were comparable in the two catchments, but those of DIN were several-fold higher in the Seybouse (373 kg N km 2 yr 1). The inner Bay affected by the Seybouse inputs had high levels of all nutrients, while the Mafragh plume and the outer marine station were less enriched.Item Diversity of the terrestrial gastropods in the Northeast Algeria: Spatial and temporal distribution(researchgate, 2013) Rabah LarbaaABSTRACT A survey of terrestrial gastropods was carried out monthly in three sites located in the Northeast Algeria (El Hadjar, Sidi Kaci, El Kala) during the period of February 2010 January 2011. The sites were chosen according to their proximity of factories and other potential sources of pollution. Totally 8463 individuals were collected and 14 species identified (12 species of snails and 2 species of slugs) belonging to six families: Milacidae, Helicidae, Subulinidae, Cochlicellidae, Enidae and Hygromiidae. Among the species identified 4 are constant: Helix aspersa (Müller, 1774), Otala lactea (Müller, 1774), Trochoidea elegans (Gmelin, 1791), Rumina decollate (Linnaeus, 1758), 3 are accessory: Helix aperta (Born, 1778), Helicella virgata (Da Costa, 1780) and Theba pisana (Müller, 1774), and 7 are accidental: Cepaea vendobonensis (Ferussac, 1821), Zebrina detrita (Müller, 1774), Dupotetia A zonata (Pallary, 1926), Cochlicella barbara (Linnaeus, 1758), Milax gagates (Draparnaud, 1801), Milax nigricans (Phillipi, 1836), Cepaea nemoralis (Linnaeus, 1758). The specific richness of the gastropod species was found to vary between sites and by season. General seasonal peak was recorded during Spring and Winter while the lowest abundance observed during Summer. Helix aspersa is the most abundant species in all prospected sites and will be used as a bioindicator of soil pollution.Item RECHERCHEDosage des marqueurs tumoraux CYFRA 21-1 et ACEdans le cancer du nasopharynx en Algérie(elsevier, 2013-03-09) BENDJEMANA KATIANasopharyngeal cancer is one of the most important cancers in our country. It ischaracterized by the influence of different etiologic factors: viral, genetic and environmental.Its diagnosis is delayed by lack of specific tumor markers. The aim of this study was to evaluatethe importance of the use of CYFRA 21-1 and ACE markers in nasopharyngeal carcinoma (NPC).Our prospective study interested 164 patients (132 M, 32 F) with a mean age of 47 years (13 to 70)with 24 of them aged less than 30 years, presenting a nasopharyngeal carcinoma histologicallyconfirmed and 180 healthy controls without evident neoplasm. Undifferentiated forms represent93% of cases. A blood sample was collected from each patient and control before any treatment,as well as controls to measure CYFRA 21-1 and ACE by immunoenzymatic assay. The resultsshowed that the mean serum CYFRA 21-1 values were significantly higher in patients with NPCthan those in controls (P ± 0.001). A significant correlation was found only between the serumCYFRA 21-1 level before treatment and the clinical outcome of patients (P ± 0.0009). Seric levelof CYFRA 21-1 at diagnosis of NPC may play a predictive role to evaluate the risk of metastaticdisease and prognosis.