Browsing by Author "Sofiane Habibatni"

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    Ajwain (Trachyspermum ammi L.) Oils
    (elsevier, 2016) Sofiane Habibatni
    This book provides an authoritative synopsis of many of the complex features of the essential oils as applied to food science, ranging from production and harvesting, to the anti-spoilage properties of individual components. It embraces a holistic approach to the topic, and is divided into two distinct parts, the general aspects and named essential oils. With more than 100 chapters in parts two and three, users will find valuable sections on botanical aspects, usage and applications, and a section on applications in food science that emphasizes the fact that essential oils are frequently used to impart flavor and aroma. However, more recently, their use as anti-spoilage agents has been extensively researched. Explains how essential oils can be used to improve safety, flavor, and function Embraces a holistic approach to the topic, and is divided into two distinct parts, the general aspects and named essential oils Provides exceptional range of information, from general use insights to specific use and application information, along with geographically specific information Examines traditional and evidence-based uses Includes methods and examples of investigation and application
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    Antioxidant and antibacterial activity of extract and phases from stems of Spartium junceum L. growing in Algeria
    (International Journal of Phytomedicineb, 2016) Sofiane Habibatni
    A b s t r a c t This work aimed to evaluate the antioxidant and antibacterial activities of the hydroalcoholic (80% methanol) extract and n-hexane (n-Hex), chloroform (Chl), ethyl acetate (EtAc), and nbutanol (n-But) phases from Spartium junceum L. stems collected in Algeria. Preliminary phytochemical investigations on phenolic compounds have been carried out. The total phenolic content, spectrophotometrically determined, ranged from 71.8095 ± 3.7136 mg GAE/g (extract) to 0.0582 ± 0.0106 mg GAE/g (n-Hex). By HPLC-PDA analysis flavonoids (flavone derivatives), p-hydroxybenzoic acid, p-hydroxycinnamic acid, and cinnamic acid derivatives were identified both in the extract and phases. S. junceum extract showed a noticeable free radical scavenging effect in the DPPH test (IC50 = 0.6833 ± 0.0240 mg/mL), mild reducing power, and strong chelating activity (IC50 = 0.2292 ± 0.0138 mg/mL). Among the phases, n-But displayed the best effect both in the DPPH test and reducing power assay, whereas n-Hex resulted the most active in the ferrous ions chelating activity assay. A positive relationship between DPPH radical scavenging activity and total phenolic content was found. Both the extract and phases exhibited antimicrobial activity against Gram-positive bacteria only. Staphylococcus aureus ATCC 6538 was the most susceptible strain (MIC range: 15.60-250.00 μg/mL), and the Chl phase showed the greatest efficacy. S. junceum extract resulted non-toxic against Artemia salina. The obtained results demonstrate the potential of S. junceum stems as safe sources of natural antioxidant and antimicrobial compounds
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    Evaluation of putative cytotoxic activity of crude extracts from Onopordum acanthium leaves and Spartium junceum flowers against the U-373 glioblastoma cell line
    (researchgate, 2015-07) Sofiane Habibatni
    Abstract: Crude hydromethanolic (80% methanol) extracts produced by maceration of Onopordum acanthium leaves and Spartium junceum flowers were tested for cytotoxic effects against glioblastoma U-373 tumour cells. Onopordum acanthium extract was found to be ~5 times more cytotoxic than Spartium junceum (IC50 values of 309 and 1602μg/ml, respectively). Similar to most chemotherapeutic agents killing through the intrinsic pathway, Onopordum killed the cells via apoptosis, which was confirmed by the activation of caspase-3. Spartium exerted its weak cytotoxic effect, presumably by a caspase-independent, non-apoptotic form of necrotic-like programmed cell death. Onopordum acanthium is considered a promising plant for the researchers investigating putative biological activities, particularly antitumour and immune-related activity
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    Preliminary study to assess cicatrizing activity of honey and Pistacia lentiscus fatty oil mixture on experimental burns in rabbits
    (researchgate, 2012-08-20) Sofiane Habibatni
    Abstract: The present study was undertaken to asses cicatrizing activity of a mixture of honey and Pistacia lentiscus fatty oil (PLFO) on dermal burn wounds. It was carried out on 8 male adult New Zealand rabbits. After anesthesia, 4 equal burns were realized on the back of each animal (2 dorsal and 2 lumbar). The wounds were treated, immediately after burning and repeated once daily until 22nd day of experiment, by 0.5 g of honey, 0.5 ml of PLFO or 0.5 g of mixture Honey + PLFO (v/v), the last wound was treated by 0.5 g of Cicatryl® as a reference drug. The healing process was evaluated by calculating the percentage of wound contraction at days 2, 6, 10, 14, 18 and 22. The results showed that both of honey, PLFO and the mixture honey + PLFO promote significantly (P<0.05) the wound contraction when compared to the standard drug at the different time intervals. In addition, PLFO showed better contraction than honey during the inflammatory and proliferative phases. The mixture showed a percentage of wound contraction better than that of honey but lower than that of PLFO used separately during the inflammatory phase, this difference became non significant at day 10 (P>0.05) and marked a significant reduction at the 14th day (P<0.05). After that the differences were not statically significant (P>0.05).In conclusion, the current study suggests that PLFO may ameliorate the healing properties of honey when mixed to it during the inflammatory phase of cicatrizing process in rabbit model