Browsing by Author "GOLEA, Lynda"

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    Green Synthesis of Azomethine Compounds
    (2026) GOLEA, Lynda
    This work presents the synthesis and spectroscopic characterization of three azomethine derivatives also known as Schiff bases, obtained by condensation of two aromatic amines (4-aminophenol and sulfanilamide) with two carbonyl compounds (benzaldehyde and acetophenone) under eco-friendly conditions. The reactions were carried out under reflux in ethanol using acetic acid as a catalyst, in accordance with the principles of green chemistry. The three synthesized compounds (SB1-SB3) were characterized by Thin-Layer Chromatography (TLC), UV–Visible spectroscopy, Fourier-Transform Infrared spectroscopy (FT-IR), and Proton Nuclear Magnetic Resonance (¹H NMR) spectroscopy. The formation of the imine bond (C=N) was confirmed in each case by the disappearance of the carbonyl C=O stretch and primary amine N–H bands in the FT-IR spectra, and by the characteristic azomethine proton signal in the ¹H NMR spectra. For the sulfanilamide-derived compound (SB-3), the reaction proceeded selectively at the primary aromatic amine group rather than at the less nucleophilic sulfonamide nitrogen. The results confirm that TLC, UV–Vis, FT-IR, and ¹H NMR together constitute a reliable and complementary toolkit for structural elucidation of azomethine compounds. The synthesized Schiff bases represent promising candidates for further investigation of their biological and coordination chemistry properties.